Global Youth Coalition on HIV/AIDS - Groups - Action Tools

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From:	Adeyemo Gabriel [ profile ]
Subject:	SA, Italy work on AIDS vaccine
Sent:	Apr 23rd, 2011 - 10:12:36

	Source:* Times (Johannesburg)* http://www.timeslive.co.za/scitech/article1030558.ece/SA-Italy-work-on-AIDS-vaccine The clinical trial for what has become known as the "Italian vaccine" will test the candidate vaccine to see if the focus by researchers at Italy's National Aids Centre (CNAIDS) on the Tat-1 protein works. Researchers believe that Tat is a gene of HIV that regulates production of the virus. This is according to the website www.hiv1tat-vaccines.info, which explains that, without Tat, the virus can enter a cell in the body, but can't replicate. It is produced very early after HIV-1 infection, even before the virus becomes part of the host cell's genetic machinery, and is necessary for the virus to replicate and infect new cells. Acutely infected cells release it and it helps "recruit" and "activate" uninfected cells. This provides new cells for the HIV-1 virus, the most prevalent strain, to infect, helping spread the HIV infection throughout the body. According to the website, data suggests vaccination with Tat may modify the virus-host dynamics and control HIV-1 replication . This can be used in prevention and treatment, they believe. A vaccination for HIV-1 positive people is believed to result in a reduced replication of the virus and slowing down of the disease. Researchers also think it can modify the virus-host dynamics at the beginning of infection. Please click on the link to read the full article. -- Many Thanks Yours' in Prevention Science Adeyemo Damilare Gabriel Regional Focal Point - West Africa Global Youth Coalition on HIV/AID (GYCA) +234-80-6798-7317 \| gabriel (at) gyca.org www.gyca.org \| www.tigweb.org GYCA is a youth-led global network of more than 4,500 young leaders and adult allies working on youth and HIV/AIDS in 150 countries world-wide. GYCA's mission is to empower young leaders with the skills, knowledge, resources and opportunities they need to scale up HIV/AIDS interventions amongst their peers. Universal Access is possible; * Zero new HIV infections. Zero discrimination and Zero AIDS-related deaths.** *

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