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From: Muge Cevik
Subject: Re: [GYCA] Three-drug ART reduces HIV transmission risk
Sent: Jan 22nd, 2011 - 17:15:33

  Hi,

Sorry but this news article is wrongly interpreted. Already the guidelines
suggest triple-therapy for pregnant women, no one is giving mono therapy to
pregnant HIV positive women (hopefully) since the mono therapy does not have
an effect as a treatment for HIV (it has effect only for prophylaxis) plus
increase the resistance. If the CD4 count is over 350 until 28 weeks there
is no need to use ART for pregnant women but after 28 weeks even though the
CD4 count is over 350, treatment is suggested because during the child birth
the viral load needs to be undetectable.

This article is about the mono therapy that is given to the child as prophylaxis
after all the pre-cautions are taken !!!! There are some studies going on
about that at the moment! But until the triple therapy is shown to be more
effective, these pre-cautions needs to be taken; once the pregnant women
(who is obviously HIV positive) take medication, deliver the baby with
C-Section plus do not breast-feed the child there is absolutely minimal risk
of child acquiring HIV.


Best wishes,

---------
Muge Cevik,MD, MSc STIs and HIV
Regional Focal Point for Western Europe
Global Youth Coalition on HIV/AIDS

e-mail: muge (at) gyca.org
TIG: mugecevik
GSM: +44 (0) 7531993677
www.tigweb.org | www.gyca.org

Chelsea and Westminster Hospital
369, Fulham Road, London, SW10 9NH

GYCA is a youth-led global network of more than 4,500 young leaders and
adult allies working on youth and HIV and AIDS in 150 countries worldwide.
GYCA's mission is to empower young leaders with the skills, knowledge,
resources and opportunities they need to scale up HIV and AIDS interventions
amongst their peers.



On 22 January 2011 00:20, Adeyemo Gabriel wrote:

> Date: 13 January 2011
> Source:* MedPage Today*
> AUTHOR: Michael Smith
> http://www.medpagetoday.com/HIVAIDS/HIVAIDS/24327
>
> In many parts of the world, the standard for preventing mother-to-child
> transmission of HIV is a short course of a single anti-retroviral drug. But
> a large randomized trial in Africa showed that full-scale anti-retroviral
> therapy with three drugs reduces the risk of passing on the virus even
> further, researchers reported online in *The Lancet*. A year after birth,
> children born to mothers given triple-drug therapy were 43% less likely to
> have HIV than children of women given standard prophylaxis, according to
> Timothy Farley, PhD, of the World Health Organization, and colleagues in
> the
> Kesho Bora Study Group. The results of the study (and others) were the
> basis
> of a 2009 decision by the WHO to revise its international guidelines for
> anti-retroviral use by pregnant and breast-feeding women.
>
> The agency now recommends maternal triple prophylaxis -- starting from the
> second trimester of pregnancy until all exposure to breast milk has ended
> --
> even if the woman is not yet eligible for the therapy for her own health.
>
> *This article is a very interesting one on prevention science. To read
> more,
> please click the above link.
> *
> --
> Many Thanks
> Yours' in Prevention Science
>
> Adeyemo Damilare Gabriel
> Regional Focal Point - West Africa
> Global Youth Coalition on HIV/AID
> +234-80-6798-7317 | gabriel (at) gyca.org
> www.gyca.org | www.tigweb.org
>
>
> GYCA is a youth-led global network of more than 4,500 young leaders and
> adult allies working on youth and HIV/AIDS in 150 countries world-wide.
> GYCA's mission is to empower young leaders with the skills, knowledge,
> resources and opportunities they need to scale up HIV/AIDS interventions
> amongst their peers.
>
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